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HIPRAVIAR-CLON

HIPRAVIAR CLON

Live vaccine against Newcastle disease, CL/79 clon, in oral freeze-dried tablet

 

COMPOSITION PER DOSE:

Live Newcastle virus CL/79 clon 106.5 - 107.7 EID50

The use of cloned strains is a great improvement in live avian vaccines against Newcastle disease, since this makes it possible to have available a completely uniform vaccine virus population, with determined characteristics in respect to pathogenicity, minimum postvaccination reactions, absence of neutralisation by passively acquired antibodies and high immunogenic activity. These are the reasons why HIPRAVIAR CLON has been developed. This vaccine can be administered to all types of poultry without manifestations of secondary reactions and little neutralisation by passively acquired antibodies. Therefore, the active immunity conferred is longer lasting than conventional virus vaccines against Newcastle disease.

 

INDICATIONS:

Poultry: Prevention of Newcastle disease in broilers, hens and chicks intended for later use as layers and breeders.

 

ADMINISTRATION ROUTE:

Ocular-nasal, oral or spray.

Ocular-nasal: Once the freeze-dried tablet is dissolved in the diluent included (sterile distilled water), administer one drop of the vaccine (0.03 ml) per bird, in the eye or nare, using a standard dropper (normally 30 ml per 1,000 doses).

Oral: Dissolve the freeze-dried tablet by ­lling the ‑ask in which it is contained to half volume with fresh tap water, shake and pour it into an adequate container up to a volume of drinking water that can be ingested within ½ or 1 hour

at most, keeping in mind that:

          Age of the bird                                           Approx. amount of water for 1,000 birds

           1 to 3 weeks                                                                      5-10 litres

           4 to 9 weeks                                                                     12-23 litres

          10 to 16 weeks                                                                  27-37 litres

 

Spray:

Validate the apparatus to be used to check the necessary amount of water. To do this, ­ll the apparatus with

fresh tap water and spray the surface which birds occupy, in a manner so that the heads of all the birds are covered with droplets of water. Check the quantity of water used, and this will be the amount that will have to be used to mix with the necessary doses, depending on the number of birds to be vaccinated. The following volumes are

 

Orientational:

                 No. of doses                         1-day-old chicks (large drops)                    Older birds (fine drops)

                       1,000                                              200-250 ml                                              500-1,000 ml

DOSAGE:

Poultry: 1 dose/bird.

- The veterinary surgeon will establish the most suitable vaccination programme according to the health conditions ofeach farm and area.

- Birds can be vaccinated 1 day after hatching, if they are placed into an endemic area of Newcastle disease.

- If the number of birds does not coincide with the number of doses of available vials, an overdose should be administered, never administer less than the recommended dosage.

 

WITHDRAWAL PERIOD:

0 days.

 

CONTRAINDICATIONS:

None.

 

ADVERSE REACTIONS:

Respiratory symptoms may occur in vaccinated birds at 5-7 days post-vaccination.

 

OBSERVATIONS:

- To ensure that vaccine water is ingested within a ½ or 1 hour at most, it is advisable not to administer water toanimals for one hour before vaccination in the summer and for 2 hours in winter.

- When administering the vaccine by spray, it is advisable to use course spray (larger than 50 microns) for ­rstvaccinations. For revaccinations, ­ner droplets can be applied (smaller than 50 microns).

 

SPECIAL PRECAUTIONS:

- Shake gently until complete resuspension of the freeze-dried tablet before administration.

- In case of administration by oral route, do not use water with chlorine or disinfectants.

- Spray administration requires the use of protective mask and glasses.

- Store at +2 to +8 °C, protected from light.

- Treat the disposable materials by boiling, incineration or immersion in a suitable disinfectant, which has beenauthorised by the competent authorities.

 

PRESENTATION:

Pack with 10 vials of 1,000 ds.

Pack with 10 vials of 2,500 ds.

Pack with 10 vials of 5,000 ds.




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