Penstrep-400

Suspension for parenteral administration

Composition:

Contains per ml:

Procaine penicillin G..............................................................................200 000.

IU. Dihydrostreptomycin sulphate .......................................................200 mg.

Excipients ad .........................................................................................1 ml.

Description:

The combination of procaine penicillin G and dihydrostreptomycin acts additive and in some cases synergistic. Procaine penicillin G is a small-spectrum penicillin with a bactericidal action against mainly Gram-positive bacteria like Clostridium, Corynebacterium, Erysipelothrix, Listeria, penicillinase-negative Staphylococcus and Streptococcus spp. Dihydrostreptomycin is an aminoglycoside with a bactericidal action against mainly Gram-negative bacteria like E. coli, Campylobacter, Klebsiella, Haemophilus, Pasteurella and Salmonella spp.

Indications:

Arthritis, mastitis and gastrointestinal, respiratory and urinary tract infections caused by penicillin and dihydrostreptomycin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Klebsiella, Listeria, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. in calves, cattle, goats, sheep and swine.

Contra-indications:

 Hypersensitivity to penicillins, procaine and/or aminoglycosides. Administration to animals with a seriously impaired renal function. Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.

Side effects:

Administration of therapeutic dosages of procaine penicillin G can result in abortion in sows. Ototoxity, neurotoxicity or nephrotoxicity. Hypersensitivity reactions.

Dosage:

For intramuscular administration:

 Cattle : 1 ml per 20 kg body weight for 3 days.

Calves, goats, sheep and swine : 1 ml per 10 kg body weight for 3 days.

Note: Shake well before use and do not administer more than 20 ml in cattle, more than 10 ml in swine and more than 5 ml in calves, sheep and goats per injection site.

Withdrawal times:

 - For kidney : 45 days.

 - For meat : 21 days.

 - For milk : 3 days.

Packaging:

Vial of 50 and 100 ml.