HIPRAVIAR B1/H120
Live vaccine, Newcastle disease, B1 strain, and Infectious bronchitis, H120 strain
QUALITATIVE AND QUANTITATIVE COMPOSITION OF THE ACTIVE SUBSTANCE:
One dose (0.03 ml) contains:
Live Newcastle Virus, B1 strain: 106.5 - 107.8 EID50*
Live Infectious Bronchitis Virus, H120 strain: 103 - 105 EID50*
* 50% infective dose in chicken embryos.
INDICATIONS FOR USE:
For the active immunization of broilers, breeders and layers to prevent Newcastle disease and Infectious Bronchitis in broilers, hens and chicks intended for later use as layers and breeders.
CONTRA-INDICATIONS:
None.
ADVERSE REACTIONS:
None.
If you notice any serious effects not mentioned in this leaet, please inform your veterinarian.
TARGET SPECIES:
Poultry (broilers, breeders and layers).
POSOLOGY FOR EACH TARGET SPECIES, METHOD AND ROUTES OF ADMINISTRATION:
Poultry: 1 dose/bird. Via ocular-nasal, administration in the drinking water and spray. The veterinary surgeon will establish the most suitable vaccination programme according to the health conditions of each farm and area.
ADVICE ON CORRECT ADMINISTRATION:
Ocular-nasal: To obtain 1,000 doses, mix 32 ml of solvent and lyophilized using the decanted supplied and gently shake until complete reconstitution of lyophilized prior to administration. Administer one drop of the vaccine (0.03 ml) per bird, in the eye or nare, using the supplied dropper.
Drinking water: Dissolve the freeze-dried powder by ‑lling the ask in which it is contained to half volume with fresh tap water, shake and pour it into an adequate container up to a volume of drinking water that can be ingested within ½ or 1 hour at most, keeping in mind that:
Age of the bird Approx. amount of water for 1,000 birds
1 to 3 weeks 5-10 litres
4 to 9 weeks 12-23 litres
10 to 16 weeks 27-37 litres
Avoid high temperatures in water where the freeze-dried fraction is diluted. To ensure that vaccine water is ingested within a ½ hour or 1 hour at most. It is advisable not to administer water to animals for one hour before vaccination in the summer and for 2 hours in winter. Do not use chlorinated water or with disinfectants, fresh tap water only.
Nebulisation: Validate the apparatus to be used for checking the necessary amount of water, as it totally depends on the type of apparatus and the size of drop it produces. To do so, ‑ll that apparatus with fresh tap water the day before vaccination and spray it on the birds in such a way that all of their heads are covered with drops of water. Check the quantity of water used and this will be the amount that will have to be used to mix with the necessary doses, depending on the number of birds to be vaccinated. The following volumes are orientational:
No. of doses 1-day-old chicks (large drops) Older birds (fine drops)
1,000 200-250 ml 500-1,000 ml
It is advisable to use course spray (larger than 50 microns) for ‑rst vaccinations. For revaccinations, ‑ner droplets can be applied (smaller than 50 microns).
WITHDRAWAL PERIOD:
0 days.
SPECIAL PRECAUTIONS FOR STORAGE:
Keep out of the reach and sight of children. Store and transport refrigerated (+2 to +8 ºC). Do not freeze. Protected from light.
SPECIAL WARNINGS:
Special warnings for each target species
Vaccinate only healthy animals. If the number of birds does not coincide with the number of doses of available vials, an overdose should be administered, never administer less than the recommended dosage. Birds can be vaccinated 1 day after hatching, if they are placed into an endemic area of Newcastle disease. Ensure that each bird received minimum one dose.
Special precautions for use in animals
Check the shelf life of the product.
Special precautions to be taken by the person administering the medicinal product to animals
Nebulisation administration requires the use of protective mask and glasses.
Use during pregnancy, lactation or lay
Do not use in birds during lay.
Interactions with other vaccines and medicinal products when administered in combination with the product:
No information is available on the safety and ef‑cacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Overdose (symptoms, emergency procedures, antidotes), if necessary:
None has been described when administered 10 times the recommended dose.
Incompatibilities:
In the absence of studies supports, do not mix with any other veterinary medicinal product.
SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED MEDICINAL PRODUCT OR WASTE MATERIALS DERIVED
FROM THE USE OF SUCH PRODUCTS:
Medicines should not be removed in sewage pouring or by household waste. Ask your veterinarian or pharmacist how to dispose unused medicines. These measures are designed to protect the environment.
OTHER INFORMATION:
Pack sizes:
Pack with 10 vials of 1,000 doses.
Pack with 10 vials of 2,500 doses.
Pack with 10 vials of solvent of 1,000 doses.
Not all pack sizes may be marketed.